Blood Urea Nitrogen (BUN) is independently associated with mortality in critically ill patients admitted to ICU.

ABSTRACT:

Purpose

Blood urea nitrogen (BUN) was reported to be associated with mortality in heart failure patients. We aimed to evaluate admission BUN concentration in a heterogeneous critically ill patient collective admitted to an intensive care unit (ICU) for prognostic relevance.

Methods

A total of 4176 medical patients (67±13 years) admitted to a German ICU between 2004 and 2009 were included. Follow-up of patients was performed retrospectively between May 2013 and November 2013. Association of admission BUN and both intra-hospital and long-term mortality were investigated by Cox regression. An optimal cut-off was calculated by means of the Youden-Index.

Results

Patients with higher admission BUN concentration were older, clinically sicker and had more pronounced laborator

SUBMITTER: Arihan O 

PROVIDER: S-EPMC5784990 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature