Genome-wide characterization of genetic variants and putative regions under selection in meat and egg-type chicken lines.

ABSTRACT:

Background

Meat and egg-type chickens have been selected for several generations for different traits. Artificial and natural selection for different phenotypes can change frequency of genetic variants, leaving particular genomic footprints throghtout the genome. Thus, the aims of this study were to sequence 28 chickens from two Brazilian lines (meat and white egg-type) and use this information to characterize genome-wide genetic variations, identify putative regions under selection using Fst method, and find putative pathways under selection.

Results

A total of 13.93 million SNPs and 1.36 million INDELs were identified, with more variants detected from the broiler (meat-type) line. Although most were located in non-coding regions, we identified 7255 intolerant non-synonymou

SUBMITTER: Boschiero C 

PROVIDER: S-EPMC5785814 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature