Variability in phase and amplitude of diurnal rhythms is related to variation of mood in bipolar and borderline personality disorder.

ABSTRACT: Variable mood is an important feature of psychiatric disorders. However, its measurement and relationship to objective measureas of physiology and behaviour have rarely been studied. Smart-phones facilitate continuous personalized prospective monitoring of subjective experience and behavioural and physiological signals can be measured through wearable devices. Such passive data streams allow novel estimates of diurnal variability. Phase and amplitude of diurnal rhythms were quantified using new techniques that fitted sinusoids to heart rate (HR) and acceleration signals. We investigated mood and diurnal variation for four days in 20 outpatients with bipolar disorder (BD), 14 with borderline personality disorder (BPD) and 20 healthy controls (HC) using a smart-phone app, portable electrocar

SUBMITTER: Carr O 

PROVIDER: S-EPMC5786095 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature