Susceptibility tensor imaging and tractography of collagen fibrils in the articular cartilage.

ABSTRACT:

Purpose

To investigate the B₀ orientation-dependent magnetic susceptibility of collagen fibrils within the articular cartilage and to determine whether susceptibility tensor imaging (STI) can detect the 3D collagen network within cartilage.

Methods

Multiecho gradient echo datasets (100-μm isotropic resolution) were acquired from fixed porcine articular cartilage specimens at 9.4 T. The susceptibility tensor was calculated using phase images acquired at 12 or 15 different orientations relative to B₀ . The susceptibility anisotropy of the collagen fibril was quantified and diffusion tensor imaging (DTI) was compared against STI. 3D tractography was performed to visualize and track the collagen fibrils with DTI and STI.

Results

STI experiments showe

SUBMITTER: Wei H 

PROVIDER: S-EPMC5786159 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature