Oncocytic Adrenocortical Neoplasm with Concomitant Papillary Thyroid Cancer.

ABSTRACT: Adrenal oncocytoma (AO) is an extremely rare adrenocortical neoplasm and little is known about its malignant potential, secretory properties, and hereditary origin. We present the case of a benign AO with concomitant incidentally found papillary thyroid cancer (PTC) and review similar cases in the literature. Immunohistochemistry and next-generation sequencing (NGS) were performed. A 66-year-old women was incidentally found to have a large, androgen-secreting right adrenal mass. ¹⁸F-Fluorodeoxyglucose positron emission tomography showed intense uptake (SUV_max 88.7) of this mass and found a hypermetabolic right thyroid mass. Open adrenalectomy was performed for this highly suspicious adrenal mass. Histopathology revealed benign AO that was BRAF^V600E negative

SUBMITTER: Podetta M 

PROVIDER: S-EPMC5786566 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature