Pregabalin Did Not Improve Pain Management After Spinal Fusions.

ABSTRACT:

Background

The treatment of postoperative pain is a challenge after posterior spinal fusions. Pain management using predominantly opioids is often associated with multiple adverse effects, while multimodal postoperative analgesia may provide adequate pain relief with fewer opioid side effects.

Questions/purposes

The purpose of this review is to determine whether addition of 150 mg pregabalin daily would reduce narcotic requirements and improve outcomes after posterior lumbar fusion (PLF).

Methods

The method used is a randomized, controlled trial of elective PLF patients who received pregabalin or placebo. With institutional review board (IRB) approval, 86 patients undergoing elective posterior lumbar fusion, ASA I-III, were randomized to receive either a placebo or pr

SUBMITTER: Urban MK 

PROVIDER: S-EPMC5786595 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature