Multicenter Evaluation of the Vitek MS v3.0 System for the Identification of Filamentous Fungi.

ABSTRACT: Invasive fungal infections are an important cause of morbidity and mortality affecting primarily immunocompromised patients. While fungal identification to the species level is critical to providing appropriate therapy, it can be slow and laborious and often relies on subjective morphological criteria. The use of matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry has the potential to speed up and improve the accuracy of identification. In this multicenter study, we evaluated the accuracy of the Vitek MS v3.0 system in identifying 1,601 clinical mold isolates compared to identification by DNA sequence analysis and supported by morphological and phenotypic testing. Among the 1,519 isolates representing organisms in the v3.0 database, 91% (n = 1,387) were

SUBMITTER: Rychert J 

PROVIDER: S-EPMC5786734 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature