A case of hypertrophic herpes simplex virus affecting the eyelid and cornea masquerading as IgG4-related disease.

ABSTRACT:

Purpose

To report a case of hypertrophic herpes simplex virus (HSV) of the eyelid and cornea masquerading as IgG4-related disease.

Observations

A 37-year old African American female with a past medical history of human immunodeficiency virus (HIV) on highly active antiretroviral therapy (HAART) and a recent history of treated genital herpes, presented with an ulcerative lesion of the left upper and lower eyelids, and severe ocular inflammation with symblepharon. Initially, eyelid biopsy revealed findings consistent with IgG4-related disease, and the patient was treated with high dose oral prednisone. After one week of therapy, there was no improvement in the patient's symptoms, and she subsequently developed a corneal epithelial defect which progressed to chronic ulceration.

SUBMITTER: Dua P 

PROVIDER: S-EPMC5786855 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature