Decreased Clinical Severity of Strangles in Weanlings Associated with Restricted Seroconversion to Optimized Streptococcus equi ssp equi Assays.

ABSTRACT:

Background

Streptococcus equi ssp. equi causes characteristic clinical signs that are most severe in young horses, including fever, purulent nasal discharge, and lymph node abscessation in the head region.

Hypothesis/objectives

Clinical, serologic, and microbiologic factors related to unexpectedly mild disease severity in a natural outbreak of strangles in immunologically naïve weanlings were investigated.

Animals

One-hundred and twelve warmblood weanlings.

Methods

Prospective longitudinal observational study of a natural outbreak of strangles. The entire cohort was examined at the peak of the outbreak by deep nasal swabs for culture and quantitative PCR (qPCR) for the presence of S. equi and clinically and serologically in a sequential manner by an optimized E

SUBMITTER: Tscheschlok L 

PROVIDER: S-EPMC5787152 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature