Differences in Epidural Pathology between Cervical and Thoracolumbar Intervertebral Disk Extrusions in Dogs.

ABSTRACT:

Background

Although the basic pathophysiology is the same in both cervical and thoracolumbar intervertebral disk (IVD) extrusions, there are considerable clinical differences that have only been partially explained.

Hypothesis/objectives

The epidural inflammatory response differs between cervical and thoracolumbar IVD extrusions.

Animals

Fifty-five dogs with cervical and 80 dogs with thoracolumbar IVD extrusions.

Methods

Clinical data and histopathologic variables were investigated. Associations between severity of epidural inflammation and clinical and pathologic variables, impact of chondrodystrophic phenotype, and localization (cervical versus thoracolumbar) were evaluated statistically.

Results

Dogs with cervical IVD extrusion were significantly olde

SUBMITTER: Zuger L 

PROVIDER: S-EPMC5787202 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature