Genomic selection models for directional dominance: an example for litter size in pigs.

ABSTRACT:

Background

The quantitative genetics theory argues that inbreeding depression and heterosis are founded on the existence of directional dominance. However, most procedures for genomic selection that have included dominance effects assumed prior symmetrical distributions. To address this, two alternatives can be considered: (1) assume the mean of dominance effects different from zero, and (2) use skewed distributions for the regularization of dominance effects. The aim of this study was to compare these approaches using two pig datasets and to confirm the presence of directional dominance.

Results

Four alternative models were implemented in two datasets of pig litter size that consisted of 13,449 and 11,581 records from 3631 and 2612 sows genotyped with the Illumina PorcineSN

SUBMITTER: Varona L 

PROVIDER: S-EPMC5787328 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature