Variants in the APOB gene was associated with Ischemic Stroke susceptibility in Chinese Han male population.

ABSTRACT:

Background

Stroke is an extremely complicated disease caused by multiple factors. Epidemiological studies have shown that genetic factors contribute to the pathogenesis of stroke. There is still little research on the effect of ApoB gene on stroke in Chinese Han population. The purpose of our research was to explore the effect of ApoB gene polymorphism on the genetic susceptibility to Ischemic Stroke in Chinese Han male population.

Materials and methods

7 polymorphisms in ApoB gene were selected and genotyped using Sequenom MassARRAY in 325 ischemic stroke male patients and 399 healthy male controls in Chinese Han population. The association between ApoB gene and genetic susceptibility to Ischemic Stroke was performed by the χ² test, ge

SUBMITTER: Zhou F 

PROVIDER: S-EPMC5788636 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature