Increased risk of venous thromboembolism associated with polymyositis and dermatomyositis: a meta-analysis.

ABSTRACT:

Objective

Polymyositis and dermatomyositis (PM/DM) have been implicated in the development of venous thromboembolism (VTE). Previous studies investigating the association between PM/DM and VTE risk had yielded inconsistent findings. The aim of this study was to precisely estimate this association by meta-analysis of all available publications.

Methods

Two investigators independently performed a comprehensive literature search in databases of PubMed, Embase, and the Cochrane Library for eligible studies. The strength for the association was weighed by pooled odds ratios (ORs) with 95% confidence intervals (95% CIs). Stratified analysis and sensitivity analysis were performed for further analysis.

Results

Six studies including 9,045 patients with PM/DM were analyzed. Th

SUBMITTER: Li Y 

PROVIDER: S-EPMC5788999 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature