The impact of long-term moderate and heavy alcohol consumption on incident atherosclerosis among persons living with HIV.

ABSTRACT:

Background

Level of alcohol consumption is associated with differential risk of atherosclerosis, but little research has investigated this association among HIV+ persons. We evaluated the association between long-term alcohol use and incident atherosclerosis among HIV+ persons.

Methods

We utilized data from HIV+ participants of the Women's Interagency HIV Study (n=483) and the Multicenter AIDS Cohort Study (n=305) without history of cardiovascular disease. Atherosclerosis was assessed two times by B-mode carotid artery ultrasound imaging from 2004 to 2013. Presence of plaque was defined as focal carotid intima-media thickness over 1.5mm. Those with no plaque at baseline and plaque at follow-up were considered incident cases of atherosclerosis. Group-based trajectory models w

SUBMITTER: Kelso-Chichetto NE 

PROVIDER: S-EPMC5789452 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature