A fluorescent activatable probe for imaging intracellular Mg2+ .

ABSTRACT: An activatable BODIPY probe for in vitro detection and fluorescence cell imaging of free Mg2+ without interference from Ca2+ is described. Fluorescence amplification of the probe is observed upon detection of physiological concentrations of Mg2+ due to reduced rotation of the fluorophore and effective chelation by a quinolizine-based core.

SUBMITTER: Treadwell R 

PROVIDER: S-EPMC5789582 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature