Priming production: Neural evidence for enhanced automatic semantic activity preceding language production in schizophrenia.

ABSTRACT:

Introduction

Lexico-semantic disturbances are considered central to schizophrenia. Clinically, their clearest manifestation is in language production. However, most studies probing their underlying mechanisms have used comprehension or categorization tasks. Here, we probed automatic semantic activity prior to language production in schizophrenia using event-related potentials (ERPs).

Methods

19 people with schizophrenia and 16 demographically-matched healthy controls named target pictures that were very quickly preceded by masked prime words. To probe automatic semantic activity prior to production, we measured the N400 ERP component evoked by these targets. To determine the origin of any automatic semantic abnormalities, we manipulated the type of relationship between prime

SUBMITTER: Kuperberg GR 

PROVIDER: S-EPMC5789757 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature