The peri-Sylvian cortical network underlying single word repetition revealed by electrocortical stimulation and direct neural recordings.

ABSTRACT: Verbal repetition requires the coordination of auditory, memory, linguistic, and motor systems. To date, the basic dynamics of neural information processing in this deceptively simple behavior are largely unknown. Here, we examined the neural processes underlying verbal repetition using focal interruption (electrocortical stimulation) in 58 patients undergoing awake craniotomies, and neurophysiological recordings (electrocorticography) in 8 patients while they performed a single word repetition task. Electrocortical stimulation revealed that sub-components of the left peri-Sylvian network involved in single word repetition could be differentially interrupted, producing transient perceptual deficits, paraphasic errors, or speech arrest. Electrocorticography revealed the detailed spatio-temp

SUBMITTER: Leonard MK 

PROVIDER: S-EPMC5790638 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature