Orthogonal decomposition of left ventricular remodeling in myocardial infarction.

ABSTRACT:

Background

Left ventricular size and shape are important for quantifying cardiac remodeling in response to cardiovascular disease. Geometric remodeling indices have been shown to have prognostic value in predicting adverse events in the clinical literature, but these often describe interrelated shape changes. We developed a novel method for deriving orthogonal remodeling components directly from any (moderately independent) set of clinical remodeling indices.

Results

Six clinical remodeling indices (end-diastolic volume index, sphericity, relative wall thickness, ejection fraction, apical conicity, and longitudinal shortening) were evaluated using cardiac magnetic resonance images of 300 patients with myocardial infarction, and 1991 asymptomatic subjects, obtained from the C

SUBMITTER: Zhang X 

PROVIDER: S-EPMC5791439 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature