Antibiotic prophylaxis in orthognathic surgery: A complex systematic review.

ABSTRACT:

Objective

In orthognathic surgery, antibiotics are prescribed to reduce the risk of postoperative infection. However, there is lack of consensus over the appropriate drug, the dose and duration of administration. The aim of this complex systematic review was to assess the effect of antibiotics on postoperative infections in orthognathic surgery.

Methods

Both systematic reviews and primary studies were assessed. Medline (OVID), The Cochrane Library (Wiley) and EMBASE (embase.com), PubMed (non-indexed articles) and Health Technology Assessment (HTA) publications were searched. The primary studies were assessed using GRADE and the systematic reviews by AMSTAR.

Results

Screening of abstracts yielded 6 systematic reviews and 36 primary studies warranting full text scrutiny

SUBMITTER: Naimi-Akbar A 

PROVIDER: S-EPMC5791956 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature