Low prevalence of HCV infection with predominance of genotype 4 among HIV patients living in Libreville, Gabon.

ABSTRACT:

Background

Gabon is an endemic area for human immunodeficiency virus (HIV) and hepatitis C virus (HCV) and the risk of co-infection is high.

Method

Between November 2015 and April 2016, we conducted retrospective study on HCV infection among people living with HIV/AIDS (PLHA). A total of 491 PLHA were included in this study and tested for the presence of HCV infection. HIV viral loads were obtained using the Generic HIV viral Load® assay and the CD4+ T cells count was performed using BD FACSCount™ CD4 reagents. HCV screening was performed using the MP Diagnostics HCV ELISA 4.0 kit. HCV genotypes were determined by sequence analysis of NS5B and Core regions. The Mann-Whitney test was used to compare the groups. Chi-2 test and Fisher's Exact Test were used to compare prevalenc

SUBMITTER: Ndjoyi-Mbiguino A 

PROVIDER: S-EPMC5791959 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature