Rhodol Derivatives as Selective Fluorescent Probes for the Detection of Hg^II Ions and the Bioimaging of Hypochlorous Acid.

ABSTRACT: Two sensors, 1 with a spirolactone group and 2 with a spirolactam group containing a phenyl isothiocyanate moiety, based on rhodol, were designed and synthesized in order to obtain materials with excellent optical properties for the detection of environmentally and biologically important Hg²⁺ and hypochlorous acid (HClO) ions. The crystal structure of 1 revealed two moieties, a rhodamine-like portion with a spirolactone and a fluorescein-like portion without a spirolactone. In the absence of analyte, 1 produced an optical output with a maximum absorption and emission at 475 and 570 nm, respectively, which was attributed to the fluorescein-like moiety without a spirolactone. In contrast, the rhodamine-like moiety containing a spirolactone was activated

SUBMITTER: Li L 

PROVIDER: S-EPMC5792738 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature