ProteoSign: an end-user online differential proteomics statistical analysis platform.

ABSTRACT: Profiling of proteome dynamics is crucial for understanding cellular behavior in response to intrinsic and extrinsic stimuli and maintenance of homeostasis. Over the last 20 years, mass spectrometry (MS) has emerged as the most powerful tool for large-scale identification and characterization of proteins. Bottom-up proteomics, the most common MS-based proteomics approach, has always been challenging in terms of data management, processing, analysis and visualization, with modern instruments capable of producing several gigabytes of data out of a single experiment. Here, we present ProteoSign, a freely available web application, dedicated in allowing users to perform proteomics differential expression/abundance analysis in a user-friendly and self-explanatory way. Although several non-comme

SUBMITTER: Efstathiou G 

PROVIDER: S-EPMC5793730 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature