XSuLT: a web server for structural annotation and representation of sequence-structure alignments.

ABSTRACT: The web server XSuLT, an enhanced version of the protein alignment annotation program JoY, formats a submitted multiple-sequence alignment using three-dimensional (3D) structural information in order to assist in the comparative analysis of protein evolution and in the optimization of alignments for comparative modelling and construct design. In addition to the features analysed by JoY, which include secondary structure, solvent accessibility and sidechain hydrogen bonds, XSuLT annotates each amino acid residue with residue depth, chain and ligand interactions, inter-residue contacts, sequence entropy, root mean square deviation and secondary structure and disorder prediction. It is also now integrated with built-in 3D visualization which interacts with the formatted alignment to facilitat

SUBMITTER: Ochoa-Montano B 

PROVIDER: S-EPMC5793734 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature