Cortical Functional Connectivity Evident After Birth and Behavioral Inhibition at Age 2.

ABSTRACT:

Objective

The infant temperament behavioral inhibition is a potent risk factor for development of an anxiety disorder. It is difficult to predict risk for behavioral inhibition at birth, however, and the neural underpinnings are poorly understood. The authors hypothesized that neonatal functional connectivity of the ventral attention network is related to behavioral inhibition at age 2 years beyond sociodemographic and familial factors. This hypothesis is supported by the ventral attention network's role in attention to novelty, a key feature of behavioral inhibition.

Method

Using a longitudinal design (N=45), the authors measured functional connectivity using MRI in neonates and behavioral inhibition at age 2 using the Infant-Toddler Social and Emotional Assessment. Whole-b

SUBMITTER: Sylvester CM 

PROVIDER: S-EPMC5794627 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature