Whole metagenome sequencing reveals links between mosquito microbiota and insecticide resistance in malaria vectors.

ABSTRACT: In light of the declining global malaria burden attained largely due to insecticides, a deeper understanding of the factors driving insecticide resistance is needed to mitigate its growing threat to malaria vector control programs. Following evidence of microbiota-mediated insecticide resistance in agricultural pests, we undertook a comparative study of the microbiota in mosquitoes of differing insecticide resistance status. The microbiota of wild-caught Anopheles albimanus, an important Latin American malaria vector, that were resistant (FEN_Res) or susceptible (FEN_Sus) to the organophosphate (OP) insecticide fenitrothion were characterized and compared using whole metagenome sequencing. Results showed differing composition of the microbiota and its functions between FEN_Res and FEN_Sus,

SUBMITTER: Dada N 

PROVIDER: S-EPMC5794770 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature