A statewide evaluation of seven strategies to reduce opioid overdose in North Carolina.

ABSTRACT:

Background

In response to increasing opioid overdoses, US prevention efforts have focused on prescriber education and supply, demand and harm reduction strategies. Limited evidence informs which interventions are effective. We evaluated Project Lazarus, a centralised statewide intervention designed to prevent opioid overdose.

Methods

Observational intervention study of seven strategies. 74 of 100 North Carolina counties implemented the intervention. Dichotomous variables were constructed for each strategy by county-month. Exposure data were: process logs, surveys, addiction treatment interviews, prescription drug monitoring data. Outcomes were: unintentional and undetermined opioid overdose deaths, overdose-related emergency department (ED) visits. Interrupted time-series Po

SUBMITTER: Alexandridis AA 

PROVIDER: S-EPMC5795575 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature