The genetic structure of the Belgian population.

ABSTRACT: BACKGROUND:National and international efforts like the 1000 Genomes Project are leading to increasing insights in the genetic structure of populations worldwide. Variation between different populations necessitates access to population-based genetic reference datasets. These data, which are important not only in clinical settings but also to potentiate future transitions towards a more personalized public health approach, are currently not available for the Belgian population. RESULTS:To obtain a representative genetic dataset of the Belgian population, participants in the 2013 National Health Interview Survey (NHIS) were invited to donate saliva samples for DNA analysis. DNA was isolated and single nucleotide polymorphisms (SNPs) were determined using a genome-wide SNP array of around 300

SUBMITTER: Van den Eynden J 

PROVIDER: S-EPMC5796395 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature