The spatial and temporal scales of local dengue virus transmission in natural settings: a retrospective analysis.

ABSTRACT:

Background

Dengue is a vector-borne disease caused by the dengue virus (DENV). Despite the crucial role of Aedes mosquitoes in DENV transmission, pure vector indices poorly correlate with human infections. Therefore there is great need for a better understanding of the spatial and temporal scales of DENV transmission between mosquitoes and humans. Here, we have systematically monitored the circulation of DENV in individual Aedes spp. mosquitoes and human patients from Caratinga, a dengue endemic city in the state of Minas Gerais, in Southeast Brazil. From these data, we have developed a novel stochastic point process pattern algorithm to identify the spatial and temporal association between DENV infected mosquitoes and human patients.

Methods

The algorithm comprises of: (i)

SUBMITTER: Sedda L 

PROVIDER: S-EPMC5797342 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature