Pseudodrusen and Incidence of Late Age-Related Macular Degeneration in Fellow Eyes in the Comparison of Age-Related Macular Degeneration Treatments Trials.

ABSTRACT:

Purpose

To evaluate the association between pseudodrusen and incidence of late age-related macular degeneration (AMD) in fellow eyes of patients with unilateral neovascular AMD (nAMD).

Design

Cohort study within the Comparison of AMD Treatments Trials (CATT).

Participants

Patients with neither nAMD nor geographic atrophy (GA) in the fellow eye at baseline.

Methods

Presence and type (dot, reticular, or confluent) of baseline pseudodrusen were assessed using digital color fundus photography (CFP) viewed under full color, green channel, and blue channel; red-free images; and fluorescein angiography (FA). Incidence of nAMD was based on monthly clinical examination and reading center evaluation of images at years 1 and 2. Incidence of GA was based on reading center

SUBMITTER: Zhou Q 

PROVIDER: S-EPMC5797653 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature