Hyperchloremia Is Associated With Complicated Course and Mortality in Pediatric Patients With Septic Shock.

ABSTRACT:

Objective

Hyperchloremia is associated with poor outcome among critically ill adults, but it is unknown if a similar association exists among critically ill children. We determined if hyperchloremia is associated with poor outcomes in children with septic shock.

Design

Retrospective analysis of a pediatric septic shock database.

Setting

Twenty-nine PICUs in the United States.

Patients

Eight hundred ninety children 10 years and younger with septic shock.

Interventions

None.

Measurements and main results

We considered the minimum, maximum, and mean chloride values during the initial 7 days of septic shock for each study subject as separate hyperchloremia variables. Within each category, we considered hyperchloremia as a dichotomous variable defined

SUBMITTER: Stenson EK 

PROVIDER: S-EPMC5798001 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature