Systematic review with meta-analysis: enteral nutrition therapy for the induction of remission in paediatric Crohn's disease.

ABSTRACT:

Background

Despite potential adverse-events in a paediatric population, corticosteroids are used to induce remission in paediatric Crohn's disease. Exclusive enteral nutrition also induces remission, but is infrequently used in the USA because corticosteroids are considered the superior therapy. New data have become available since the publication of the most recent meta-analysis in 2007.

Aim

To see if current literature supports the use of EEN versus CS in paediatric populations.

Methods

All studies with comparator arms of exclusive enteral nutrition and an exclusive corticosteroids, with remission clearly defined were identified by searching eight online databases.

Results

Of 2795 identified sources, nine studies met our inclusion criteria. Eight of these (n 

SUBMITTER: Swaminath A 

PROVIDER: S-EPMC5798240 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature