Risk of Clostridium difficile Infection in Patients With Celiac Disease: A Population-Based Study.

ABSTRACT:

Objectives

Patients with celiac disease are at increased risk for infections such as tuberculosis, influenza, and pneumococcal pneumonia. However, little is known about the incidence of Clostridium difficile infection (CDI) in patients with celiac disease.

Methods

We identified patients with celiac disease based on intestinal biopsies submitted to all pathology departments in Sweden over a 39-year period (from July 1969 through February 2008). We compared risk of CDI (based on stratified Cox proportional hazards models) among patients with celiac disease vs. without celiac disease (controls) matched by age, sex, and calendar period.

Results

We identified 28,339 patients with celiac disease and 141,588 controls; neither group had a history of CDI. The incidence of CDI

SUBMITTER: Lebwohl B 

PROVIDER: S-EPMC5798865 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature