Novel Quantitative Analytical Approaches for Rotor Identification and Associated Implications for Mapping.

ABSTRACT:

Goal

Clinical studies identifying rotors and confirming these sites for ablation in treating cardiac arrhythmias have had inconsistent results with the currently available analysis techniques. The aim of this study is to evaluate four new signal analysis approaches-multiscale frequency (MSF), Shannon entropy (SE), Kurtosis (Kt), and multiscale entropy (MSE)-in their ability to identify the pivot point of rotors.

Methods

Optical mapping movies of ventricular tachycardia were used to evaluate the performance and robustness of SE, Kt, MSF, and MSE techniques with respect to several clinical limitations: decreased time duration, reduced spatial resolution, and the presence of meandering rotors. To quantitatively assess the robustness of the four techniques, results were compared

SUBMITTER: Annoni EM 

PROVIDER: S-EPMC5798878 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature