Ebola RNA Persistence in Semen of Ebola Virus Disease Survivors - Final Report.

ABSTRACT:

Background

Ebola virus has been detected in the semen of men after their recovery from Ebola virus disease (EVD). We report the presence of Ebola virus RNA in semen in a cohort of survivors of EVD in Sierra Leone.

Methods

We enrolled a convenience sample of 220 adult male survivors of EVD in Sierra Leone, at various times after discharge from an Ebola treatment unit (ETU), in two phases (100 participants were in phase 1, and 120 in phase 2). Semen specimens obtained at baseline were tested by means of a quantitative reverse-transcriptase-polymerase-chain-reaction (RT-PCR) assay with the use of the target sequences of NP and VP40 (in phase 1) or NP and GP (in phase 2). This study did not evaluate directly the risk of sexual transmission of EVD.

Results

Of 210 participa

SUBMITTER: Deen GF 

PROVIDER: S-EPMC5798881 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature