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ABSTRACT: Activation of the NAIP/NLRC4 inflammasomes initiates inflammatory responses against bacterial invasion. Two recent reports described the cryo-EM structure of the flagellin/NAIP5 complex, providing important insights into the mechanism of bacterial sensing by innate immunity.
SUBMITTER: Zhang L
PROVIDER: S-EPMC5799821 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
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