Formal (4 + 1)-Addition of Allenoates to o-Quinone Methides.

ABSTRACT: The first (4 + 1)-annulation of o-quinone methides with α-branched allenoates as C1 synthons has been developed. This operationally simple protocol gives access to highly functionalized dihydrobenzofurans in an unprecedented fashion with excellent diastereoselectivities and high yields.

SUBMITTER: Zielke K 

PROVIDER: S-EPMC5799871 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature