Molecular analysis of carnivore Protoparvovirus detected in white blood cells of naturally infected cats.

ABSTRACT:

Background

Cats are susceptible to feline panleukopenia virus (FPV) and canine parvovirus (CPV) variants 2a, 2b and 2c. Detection of FPV and CPV variants in apparently healthy cats and their persistence in white blood cells (WBC) and other tissues when neutralising antibodies are simultaneously present, suggest that parvovirus may persist long-term in the tissues of cats post-infection without causing clinical signs. The aim of this study was to screen a population of 54 cats from Sardinia (Italy) for the presence of both FPV and CPV DNA within buffy coat samples using polymerase chain reaction (PCR). The DNA viral load, genetic diversity, phylogeny and antibody titres against parvoviruses were investigated in the positive cats.

Results

Carnivore protoparvovirus 1 DNA was de

SUBMITTER: Balboni A 

PROVIDER: S-EPMC5799907 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature