Association of zygotic piRNAs derived from paternal P elements with hybrid dysgenesis in Drosophila melanogaster.

ABSTRACT:

Background

P-element transposition in the genome causes P-M hybrid dysgenesis in Drosophila melanogaster. Maternally deposited piRNAs suppress P-element transposition in the progeny, linking them to P-M phenotypes; however, the role of zygotic piRNAs derived from paternal P elements is poorly understood.

Results

To elucidate the molecular basis of P-element suppression by zygotic factors, we investigated the genomic constitution and P-element piRNA production derived from fathers. As a result, we characterized males of naturally derived Q, M' and P strains, which show different capacities for the P-element mobilizations introduced after hybridizations with M-strain females. The amounts of piRNAs produced in ovaries of F1 hybri

SUBMITTER: Wakisaka KT 

PROVIDER: S-EPMC5800288 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature