Changing Odds of Survival Over Time among Patients Undergoing Surgical Resection of Gallbladder Carcinoma.

ABSTRACT:

Background

While survival after malignancies is traditionally reported as actuarial survival, conditional survival (CS) may be more clinically relevant by accounting for "accrued" survival time as time progresses. We sought to compare actuarial and CS among patients with gallbladder carcinoma (GBC) .

Methods

A total of 312 patients who underwent curative intent surgery for GBC between 2000 and 2014 were identified using a multi-institutional database. Overall survival (OS) was estimated using the Kaplan-Meier method. CS was calculated as the probability of surviving an additional 3 years at year "x" after surgery using the formula CS₃ = S_(x+3)/S_x.

Results

Among all patients, the median actuarial OS was 24.8 months (IQR 13.3-88.9). Whil

SUBMITTER: Buettner S 

PROVIDER: S-EPMC5800768 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature