Biomarkers for cognitive decline in patients with diabetes mellitus: evidence from clinical studies.

ABSTRACT: Diabetes mellitus is considered as an important factor for cognitive decline and dementia in recent years. However, cognitive impairment in diabetic patients is often underestimated and kept undiagnosed, leading to thousands of diabetic patients suffering from worsening memory. Available reviews in this field were limited and not comprehensive enough. Thus, the present review aimed to summarize all available clinical studies on diabetic patients with cognitive decline, and to find valuable biomarkers that might be applied as diagnostic and therapeutic targets of cognitive impairment in diabetes. The biomarkers or risk factors of cognitive decline in diabetic patients could be classified into the following three aspects: serum molecules or relevant complications, functional or metabolic cha

SUBMITTER: Zhao X 

PROVIDER: S-EPMC5800938 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature