Individualized outcome prognostication for patients with laryngeal cancer.

ABSTRACT:

Background

Accurate prognostication is essential to the optimal management of laryngeal cancer. Predictive models have been developed to calculate the risk of oncologic outcomes, but extensive external validation of accuracy and reliability is necessary before implementing them into clinical practice.

Method

Four published prognostic calculators that predict 5-year overall survival for patients with laryngeal cancer were evaluated using patient information from a prospective epidemiology study cohort (n = 246; median follow-up, 60 months) with previously untreated, stage I through IVb laryngeal squamous cell carcinoma.

Results

Different calculators yielded substantially different predictions for individual patients. The observed 5-year overall survival was significant

SUBMITTER: Hoban CW 

PROVIDER: S-EPMC5800991 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature