An ERP study of multidimensional source retrieval in depression.

ABSTRACT: We collected event-related potentials (ERPs) from 24 unmedicated adults with Major Depressive Disorder (MDD) and 24 controls during source memory retrieval. Words were encoded on the left or right during animacy and mobility judgments. Mobility judgments were slower than animacy judgments, suggesting deeper encoding. Participants then recalled the encoding judgment (Question cue) and position (Side cue) for each word. Depressed adults, but not controls, showed better accuracy for words from the mobility task presented under the Question vs. Side Cue. Furthermore, depressed adults showed larger left parietal ERPs to words from the mobility task presented under the Question vs. the Side Cue from 400 to 800 ms and 800-1400 ms. This ERP effect was negatively correlated with sleep quality. Thus

SUBMITTER: Barrick EM 

PROVIDER: S-EPMC5801054 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature