Prevalence of anthracycline-related cardiac dysfunction in long-term survivors of adult-onset lymphoma.

ABSTRACT:

Background

Anthracycline-related heart failure is a leading cause of morbidity in survivors of adult-onset lymphoma. There is a paucity of information on screening for late-occurring preclinical disease, which, in turn, has limited guidelines for early detection and intervention. The objectives of this study were to examine the prevalence and risk of cardiac dysfunction, as measured by echocardiography (abnormal left ventricular systolic/diastolic function or strain), in lymphoma survivors who received treatment with anthracyclines and to evaluate the diagnostic yield of blood biomarkers in the asymptomatic setting.

Methods

Lymphoma survivors who underwent hematopoietic cell transplantation (HCT) (n = 78) or received conventional therapy (non-HCT; n = 77) were compared with

SUBMITTER: Armenian SH 

PROVIDER: S-EPMC5801059 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature