When Proactivity Fails: An Electrophysiological Study of Establishing Reference in Schizophrenia.

ABSTRACT: BACKGROUND:Schizophrenia is characterized by abnormalities in referential communication, which may be linked to more general deficits in proactive cognitive control. We used event-related potentials to probe the timing and nature of the neural mechanisms engaged as people with schizophrenia linked pronouns to their preceding referents during word-by-word sentence comprehension. METHODS:We measured event-related potentials to pronouns in two-clause sentences in 16 people with schizophrenia and 20 demographically matched control participants. Our design crossed the number of potential referents (1-referent, 2-referent) with whether the pronoun matched the gender of its preceding referent(s) (matching, mismatching). This gave rise to four conditions: 1) 1-referent matching ("Edward took cours

SUBMITTER: Kuperberg GR 

PROVIDER: S-EPMC5801772 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature