Impact of liver volume on polycystic liver disease-related symptoms and quality of life.

ABSTRACT:

Background

Symptoms in polycystic liver disease (PLD) are thought to be caused by compression of organs and structures by the enlarged liver.

Aim

The aim of this article is to assess the impact of liver volume on symptoms and quality of life (QoL) in PLD.

Methods

We included PLD patients from two prospective studies that used the PLD-questionnaire (PLD-Q) for symptom assessment. QoL was assessed through SF-36, summarized in a physical (PCS) and mental (MCS) component score. Liver volume was correlated with PLD-Q total scores. Patients were classified based on height-corrected liver volume in mild (<1600 ml), moderate (1600-3200 ml), and severe (>3200 ml) disease. PLD-Q and QoL (PCS and MCS) scores were compared across disease stages.

Results

We included 82 of 1

SUBMITTER: Neijenhuis MK 

PROVIDER: S-EPMC5802666 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature