Methane utilization in Methylomicrobium alcaliphilum 20Z^R: a systems approach.

ABSTRACT: Biological methane utilization, one of the main sinks of the greenhouse gas in nature, represents an attractive platform for production of fuels and value-added chemicals. Despite the progress made in our understanding of the individual parts of methane utilization, our knowledge of how the whole-cell metabolic network is organized and coordinated is limited. Attractive growth and methane-conversion rates, a complete and expert-annotated genome sequence, as well as large enzymatic, ¹³C-labeling, and transcriptomic datasets make Methylomicrobium alcaliphilum 20Z^R an exceptional model system for investigating methane utilization networks. Here we present a comprehensive metabolic framework of methane and methanol utilization in M. alcaliphilum 20Z^R. A set of

SUBMITTER: Akberdin IR 

PROVIDER: S-EPMC5802761 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature