The relationship of Physical performance and Osteoporosis prevention with vitamin D in older African Americans (PODA).

ABSTRACT:

Rationale

Vitamin D deficiency is associated with bone loss, poor muscle strength, falls and fracture. This information in older African Americans (AAs) is sparse.

Objective

The study of the relationship of Physical performance, Osteoporosis prevention with vitamin D in older African Americans (PODA) is a randomized, double-blind, placebo-controlled 3-year trial examining the effect of vitamin D on bone loss and physical performance in older AA women.

Methods

260 healthy AA women aged >60years were assigned to receive placebo or vitamin D₃. Initial vitamin D₃ dose was determined by the baseline serum 25OHD level, and adjusted further to maintain serum 25OHD between 30 and 69ng/ml. Subjects with baseline 25OHD levels ≤8ng/ml or ≥26ng/ml were exclu

SUBMITTER: Dhaliwal R 

PROVIDER: S-EPMC5803298 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature