Adapting cervical cancer screening for women vaccinated against human papillomavirus infections: The value of stratifying guidelines.

ABSTRACT:

Background

Several countries have implemented vaccination against human papillomavirus (HPV) for adolescent girls and must decide whether and how to adapt cervical cancer (CC) screening for these low-risk women. We aimed to identify the optimal screening strategies for women vaccinated against HPV infections and quantify the amount that could be spent to identify vaccination status among women and stratify CC screening guidelines accordingly.

Methods

We used a mathematical model reflecting HPV-induced CC in Norway to project the long-term health benefits, resources and costs associated with 74 candidate-screening strategies that varied by screening test, start age and frequency. Strategies were considered separately for women vaccinated with the bivalent/quadrivalent (2/4vHP

SUBMITTER: Pedersen K 

PROVIDER: S-EPMC5803338 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature