Publication proportions for registered breast cancer trials: before and following the introduction of the ClinicalTrials.gov results database.

ABSTRACT:

Background

To limit selective and incomplete publication of the results of clinical trials, registries including ClinicalTrials.gov were introduced. The ClinicalTrials.gov registry added a results database in 2008 to enable researchers to post the results of their trials as stipulated by the Food and Drug Administration Amendment Act of 2007. This study aimed to determine the direction and magnitude of any change in publication proportions of registered breast cancer trials that occurred since the inception of the ClinicalTrials.gov results database.

Methods

A cross-sectional study design was employed using ClinicalTrials.gov, a publicly available registry/results database as the primary data source. Registry contents under the subcategories 'Breast Neoplasms' and 'Breast Ne

SUBMITTER: Asiimwe IG 

PROVIDER: S-EPMC5803577 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature