Assessing the Generalizability of the National Lung Screening Trial: Comparison of Patients with Stage 1 Disease.

ABSTRACT:

Rationale

The findings of the NLST (National Lung Screening Trial) are the basis for screening high-risk individuals according to age and smoking history. Although screening is covered for eligible Medicare beneficiaries, the generalizability of the NLST in the elderly population has been questioned.

Objectives

Compare outcomes of patients diagnosed with stage 1 non-small cell lung cancer in the NLST to a nationally representative cohort of elderly patients Methods: Analysis of Surveillance, Epidemiology, and End Results (SEER)-Medicare and NLST datasets for patients with stage 1 disease aged 65 to 74 years.

Measurements and main results

Lung cancer-specific mortality, all-cause mortality, and 30-, 60-, and 90-day treatment mortality were measured. When compared with

SUBMITTER: Tanner NT 

PROVIDER: S-EPMC5803664 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature